| 1-butene | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Toluene monooxygenase-catalyzed epoxidation of alkenes. Appl Environ Microbiol. 2000 May;66(5):1877-82.
PMID: 10788354
|
| 1-chloroethane | | Pseudomonas mendocina KR1 | + |
McClay K, Streger SH, Steffan RJ. Induction of toluene oxidation activity in Pseudomonas mendocina KR1 and Pseudomonas sp. strain ENVPC5 by chlorinated solvents and alkanes. Appl Environ Microbiol. 1995 Sep;61(9):3479-81. PubMed Central PMCID: PMC167628.
PMID: 7574658
|
| 1-hexene | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Toluene monooxygenase-catalyzed epoxidation of alkenes. Appl Environ Microbiol. 2000 May;66(5):1877-82.
PMID: 10788354
|
| 1-pentene | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Toluene monooxygenase-catalyzed epoxidation of alkenes. Appl Environ Microbiol. 2000 May;66(5):1877-82.
PMID: 10788354
|
| 1,1-diethylcyclopropane | 1-methyl-2-ethylcyclobutanol | Pseudomonas mendocina KR1 | + |
Moe LA, Hu Z, Deng D, Austin RN, Groves JT, Fox BG. Remarkable aliphatic hydroxylation by the diiron enzyme toluene 4-monooxygenase in reactions with radical or cation diagnostic probes norcarane, 1,1-dimethylcyclopropane, and 1,1-diethylcyclopropane. Biochemistry. 2004 Dec 21;43(50):15688-701. PubMed PMID:
PMID: 15595825
|
| 1,1-diethylcyclopropane | 3-methyl-3-penten-1-ol | Pseudomonas mendocina KR1 | + |
Moe LA, Hu Z, Deng D, Austin RN, Groves JT, Fox BG. Remarkable aliphatic hydroxylation by the diiron enzyme toluene 4-monooxygenase in reactions with radical or cation diagnostic probes norcarane, 1,1-dimethylcyclopropane, and 1,1-diethylcyclopropane. Biochemistry. 2004 Dec 21;43(50):15688-701. PubMed PMID:
PMID: 15595825
|
| 1,1-diethylcyclopropane | 1-(1-ethylcyclopropyl)-ethanol | Pseudomonas mendocina KR1 | + |
Moe LA, Hu Z, Deng D, Austin RN, Groves JT, Fox BG. Remarkable aliphatic hydroxylation by the diiron enzyme toluene 4-monooxygenase in reactions with radical or cation diagnostic probes norcarane, 1,1-dimethylcyclopropane, and 1,1-diethylcyclopropane. Biochemistry. 2004 Dec 21;43(50):15688-701. PubMed PMID:
PMID: 15595825
|
| 1,1-dimethylcyclopropane | 1-methylcyclopropanemethanol | Pseudomonas mendocina KR1 | + |
Moe LA, Hu Z, Deng D, Austin RN, Groves JT, Fox BG. Remarkable aliphatic hydroxylation by the diiron enzyme toluene 4-monooxygenase in reactions with radical or cation diagnostic probes norcarane, 1,1-dimethylcyclopropane, and 1,1-diethylcyclopropane. Biochemistry. 2004 Dec 21;43(50):15688-701. PubMed PMID:
PMID: 15595825
|
| 1,1-dimethylcyclopropane | 1-methylcyclobutanol | Pseudomonas mendocina KR1 | + |
Moe LA, Hu Z, Deng D, Austin RN, Groves JT, Fox BG. Remarkable aliphatic hydroxylation by the diiron enzyme toluene 4-monooxygenase in reactions with radical or cation diagnostic probes norcarane, 1,1-dimethylcyclopropane, and 1,1-diethylcyclopropane. Biochemistry. 2004 Dec 21;43(50):15688-701. PubMed PMID:
PMID: 15595825
|
| 1,1-dimethylcyclopropane | 3-methyl-3-buten-1-ol | Pseudomonas mendocina KR1 | + |
Moe LA, Hu Z, Deng D, Austin RN, Groves JT, Fox BG. Remarkable aliphatic hydroxylation by the diiron enzyme toluene 4-monooxygenase in reactions with radical or cation diagnostic probes norcarane, 1,1-dimethylcyclopropane, and 1,1-diethylcyclopropane. Biochemistry. 2004 Dec 21;43(50):15688-701. PubMed PMID:
PMID: 15595825
|
| 1,2-dichlorobenzene | | Pseudomonas mendocina KR1 | + |
Leahy JG, Tracy KD, Eley MH. Degradation of mixtures of aromatic and chloroaliphatic hydrocarbons by aromatic hydrocarbon-degrading bacteria. FEMS Microbiol Ecol. 2003 Mar 1;43(2):271-6. doi: 10.1111/j.1574-6941.2003.tb01067.x.
PMID: 19719688
|
| 1,2,4-trimethyl benzene | | Pseudomonas mendocina KR1 | + |
Leahy JG, Tracy KD, Eley MH. Degradation of mixtures of aromatic and chloroaliphatic hydrocarbons by aromatic hydrocarbon-degrading bacteria. FEMS Microbiol Ecol. 2003 Mar 1;43(2):271-6. doi: 10.1111/j.1574-6941.2003.tb01067.x.
PMID: 19719688
|
| 1,3-butadiene | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Toluene monooxygenase-catalyzed epoxidation of alkenes. Appl Environ Microbiol. 2000 May;66(5):1877-82.
PMID: 10788354
|
| 1,3-dichlorobenzene | | Pseudomonas mendocina KR1 | + |
Leahy JG, Tracy KD, Eley MH. Degradation of mixtures of aromatic and chloroaliphatic hydrocarbons by aromatic hydrocarbon-degrading bacteria. FEMS Microbiol Ecol. 2003 Mar 1;43(2):271-6. doi: 10.1111/j.1574-6941.2003.tb01067.x.
PMID: 19719688
|
| 1,3,5-trimethylbenzene | | Pseudomonas mendocina KR1 | + |
Leahy JG, Tracy KD, Eley MH. Degradation of mixtures of aromatic and chloroaliphatic hydrocarbons by aromatic hydrocarbon-degrading bacteria. FEMS Microbiol Ecol. 2003 Mar 1;43(2):271-6. doi: 10.1111/j.1574-6941.2003.tb01067.x.
PMID: 19719688
|
| 1,4-dioxane | | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Mahendra S, Alvarez-Cohen L. Kinetics of 1,4-dioxane biodegradation by monooxygenase-expressing bacteria. Environ Sci Technol. 2006 Sep 1;40(17):5435-42.
PMID: 16999122
|
| 1,4-dioxane | | Pseudomonas mendocina KR1 | + |
Mahendra S, Alvarez-Cohen L. Kinetics of 1,4-dioxane biodegradation by monooxygenase-expressing bacteria. Environ Sci Technol. 2006 Sep 1;40(17):5435-42.
PMID: 16999122
|
| 2-butene | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Toluene monooxygenase-catalyzed epoxidation of alkenes. Appl Environ Microbiol. 2000 May;66(5):1877-82.
PMID: 10788354
|
| 2-chloropropene | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Toluene monooxygenase-catalyzed epoxidation of alkenes. Appl Environ Microbiol. 2000 May;66(5):1877-82.
PMID: 10788354
|
| 2-chlorotoluene | | Pseudomonas mendocina KR1 | + |
Leahy JG, Tracy KD, Eley MH. Degradation of mixtures of aromatic and chloroaliphatic hydrocarbons by aromatic hydrocarbon-degrading bacteria. FEMS Microbiol Ecol. 2003 Mar 1;43(2):271-6. doi: 10.1111/j.1574-6941.2003.tb01067.x.
PMID: 19719688
|
| 2-naphthol | 1,7-dihydroxynaphthalene | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Bentley WE, Wood TK. Regiospecific oxidation of naphthalene and fluorene by toluene monooxygenases and engineered toluene 4-monooxygenases of Pseudomonas mendocina KR1. Biotechnol Bioeng. 2005 Apr 5;90(1):85-94.
PMID: 15723332
|
| 2-naphthol | 2,6-dihydroxynaphthalene | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Bentley WE, Wood TK. Regiospecific oxidation of naphthalene and fluorene by toluene monooxygenases and engineered toluene 4-monooxygenases of Pseudomonas mendocina KR1. Biotechnol Bioeng. 2005 Apr 5;90(1):85-94.
PMID: 15723332
|
| 2-pentene | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Toluene monooxygenase-catalyzed epoxidation of alkenes. Appl Environ Microbiol. 2000 May;66(5):1877-82.
PMID: 10788354
|
| 2,3-dichloropropene | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Toluene monooxygenase-catalyzed epoxidation of alkenes. Appl Environ Microbiol. 2000 May;66(5):1877-82.
PMID: 10788354
|
| 3-hydroxyfluorene | 3,6-dihydroxyfluorene | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Bentley WE, Wood TK. Regiospecific oxidation of naphthalene and fluorene by toluene monooxygenases and engineered toluene 4-monooxygenases of Pseudomonas mendocina KR1. Biotechnol Bioeng. 2005 Apr 5;90(1):85-94.
PMID: 15723332
|
| acetanilide | | Escherichia coli JM109 pRS202 tmoABCDEF | + |
Yen KM, Karl MR, Blatt LM, Simon MJ, Winter RB, Fausset PR, Lu HS, Harcourt AA, Chen KK. Cloning and characterization of a Pseudomonas mendocina KR1 gene cluster encoding toluene-4-monooxygenase. J Bacteriol. 1991 Sep;173(17):5315-27. PubMed Central PMCID: PMC208241.
PMID: 1885512
|
| anisole | 4-methoxyphenol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| anthracene | | Pseudomonas mendocina KR1 | + |
Oppenheim SF, Studts JM, Fox BG, Dordick JS. Aromatic hydroxylation catalyzed by toluene 4-monooxygenase in organic solvent/aqueous buffer mixtures. Appl Biochem Biotechnol. 2001 Mar;90(3):187-97.
PMID: 11318032
|
| anthrone | | Pseudomonas mendocina KR1 | + |
Oppenheim SF, Studts JM, Fox BG, Dordick JS. Aromatic hydroxylation catalyzed by toluene 4-monooxygenase in organic solvent/aqueous buffer mixtures. Appl Biochem Biotechnol. 2001 Mar;90(3):187-97.
PMID: 11318032
|
| bromobenzene | 4-bromophenol | Pseudomonas mendocina KR1 | + |
Bailey LJ, Acheson JF, McCoy JG, Elsen NL, Phillips GN Jr, Fox BG. Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 2012 Feb 14;51(6):1101-13. doi: 10.1021/bi2018333.
PMID: 22264099
|
| catechol | 1,2,3-trihydroxybenzene | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Oxidation of benzene to phenol, catechol, and 1,2,3-trihydroxybenzene by toluene 4-monooxygenase of Pseudomonas mendocina KR1 and toluene 3-monooxygenase of Ralstonia pickettii PKO1. Appl Environ Microbiol. 2004 Jul;70(7):3814-20. PubMed Central
PMID: 15240250
|
| chlorobenzene | 4-chlorophenol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| chloroform | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Chloroform mineralization by toluene-oxidizing bacteria. Appl Environ Microbiol. 1996 Aug;62(8):2716-22.
PMID: 8702263
|
| cis-1,2-dichloroethane | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Chloroform mineralization by toluene-oxidizing bacteria. Appl Environ Microbiol. 1996 Aug;62(8):2716-22.
PMID: 8702263
|
| cis-1,2-dichloroethene | | Pseudomonas mendocina KR1 | + |
McClay K, Streger SH, Steffan RJ. Induction of toluene oxidation activity in Pseudomonas mendocina KR1 and Pseudomonas sp. strain ENVPC5 by chlorinated solvents and alkanes. Appl Environ Microbiol. 1995 Sep;61(9):3479-81. PubMed Central PMCID: PMC167628.
PMID: 7574658
|
| cis-dibromoethylene | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Chloroform mineralization by toluene-oxidizing bacteria. Appl Environ Microbiol. 1996 Aug;62(8):2716-22.
PMID: 8702263
|
| ethylbenzene | | Pseudomonas mendocina KR1 | + |
Leahy JG, Tracy KD, Eley MH. Degradation of mixtures of aromatic and chloroaliphatic hydrocarbons by aromatic hydrocarbon-degrading bacteria. FEMS Microbiol Ecol. 2003 Mar 1;43(2):271-6. doi: 10.1111/j.1574-6941.2003.tb01067.x.
PMID: 19719688
|
| flavanone | | Pseudomonas mendocina KR1 | + |
Oppenheim SF, Studts JM, Fox BG, Dordick JS. Aromatic hydroxylation catalyzed by toluene 4-monooxygenase in organic solvent/aqueous buffer mixtures. Appl Biochem Biotechnol. 2001 Mar;90(3):187-97.
PMID: 11318032
|
| flavone | | Pseudomonas mendocina KR1 | + |
Oppenheim SF, Studts JM, Fox BG, Dordick JS. Aromatic hydroxylation catalyzed by toluene 4-monooxygenase in organic solvent/aqueous buffer mixtures. Appl Biochem Biotechnol. 2001 Mar;90(3):187-97.
PMID: 11318032
|
| fluorene | 3-hydroxyfluorene | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Bentley WE, Wood TK. Regiospecific oxidation of naphthalene and fluorene by toluene monooxygenases and engineered toluene 4-monooxygenases of Pseudomonas mendocina KR1. Biotechnol Bioeng. 2005 Apr 5;90(1):85-94.
PMID: 15723332
|
| fluorene | 2-hydroxyfluorene | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Bentley WE, Wood TK. Regiospecific oxidation of naphthalene and fluorene by toluene monooxygenases and engineered toluene 4-monooxygenases of Pseudomonas mendocina KR1. Biotechnol Bioeng. 2005 Apr 5;90(1):85-94.
PMID: 15723332
|
| fluorobenzene | 4-fluorocatechol | Pseudomonas mendocina KR1 | + |
Nolan LC, O'Connor KE. Use of Pseudomonas mendocina, or recombinant Escherichia coli cells expressing toluene-4-monooxygenase, and a cell-free tyrosinase for the synthesis of 4-fluorocatechol from fluorobenzene. Biotechnol Lett. 2007 Jul;29(7):1045-50.
PMID: 17426925
|
| fluorobenzene | 4-fluorophenol | Pseudomonas mendocina KR1 | + |
Nolan LC, O'Connor KE. Use of Pseudomonas mendocina, or recombinant Escherichia coli cells expressing toluene-4-monooxygenase, and a cell-free tyrosinase for the synthesis of 4-fluorocatechol from fluorobenzene. Biotechnol Lett. 2007 Jul;29(7):1045-50.
PMID: 17426925
|
| indole | 2-oxindole | Pseudomonas mendocina KR1 | + |
McClay K, Boss C, Keresztes I, Steffan RJ. Mutations of toluene-4-monooxygenase that alter regiospecificity of indole oxidation and lead to production of novel indigoid pigments. Appl Environ Microbiol. 2005 Sep;71(9):5476-83. PubMed Central PMCID: PMC1214665.
PMID: 16151140
|
| isopropylbenzene | | Pseudomonas mendocina KR1 | + |
Leahy JG, Tracy KD, Eley MH. Degradation of mixtures of aromatic and chloroaliphatic hydrocarbons by aromatic hydrocarbon-degrading bacteria. FEMS Microbiol Ecol. 2003 Mar 1;43(2):271-6. doi: 10.1111/j.1574-6941.2003.tb01067.x.
PMID: 19719688
|
| m-cresol | 4-methylcatechol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| m-cresol | 4-methylcatechol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| m-xylene | 2,4-dimethylphenol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| m-xylene | (3-methylphenyl)methanol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| m-xylene | 3,5-dimethylphenol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| methyl p-tolyl sulfide | Methyl p-tolyl sulfoxide | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Feingersch R, Shainsky J, Wood TK, Fishman A. Protein engineering of toluene monooxygenases for synthesis of chiral sulfoxides. Appl Environ Microbiol. 2008 Mar;74(5):1555-66. doi: 10.1128/AEM.01849-07. PubMed
PMID: 18192418
|
| methyl phenyl sulfide | Methyl phenyl sulfoxide | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Feingersch R, Shainsky J, Wood TK, Fishman A. Protein engineering of toluene monooxygenases for synthesis of chiral sulfoxides. Appl Environ Microbiol. 2008 Mar;74(5):1555-66. doi: 10.1128/AEM.01849-07. PubMed
PMID: 18192418
|
| N-nitrodimethylamine | N-nitromethylamine | Pseudomonas mendocina KR1 | + |
Fournier D, Hawari J, Streger SH, McClay K, Hatzinger PB. Biotransformation of N-nitrosodimethylamine by Pseudomonas mendocina KR1. Appl Environ Microbiol. 2006 Oct;72(10):6693-8. PubMed Central PMCID: PMC1610310.
PMID: 16950909
|
| N-nitrosodimethylamine | N-nitrodimethylamine | Pseudomonas mendocina KR1 | + |
Fournier D, Hawari J, Streger SH, McClay K, Hatzinger PB. Biotransformation of N-nitrosodimethylamine by Pseudomonas mendocina KR1. Appl Environ Microbiol. 2006 Oct;72(10):6693-8. PubMed Central PMCID: PMC1610310.
PMID: 16950909
|
| naphthalene | 1-naphthol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Bentley WE, Wood TK. Regiospecific oxidation of naphthalene and fluorene by toluene monooxygenases and engineered toluene 4-monooxygenases of Pseudomonas mendocina KR1. Biotechnol Bioeng. 2005 Apr 5;90(1):85-94.
PMID: 15723332
|
| naphthalene | 2-naphthol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Bentley WE, Wood TK. Regiospecific oxidation of naphthalene and fluorene by toluene monooxygenases and engineered toluene 4-monooxygenases of Pseudomonas mendocina KR1. Biotechnol Bioeng. 2005 Apr 5;90(1):85-94.
PMID: 15723332
|
| naphthalene | 1-naphthol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Bentley WE, Wood TK. Regiospecific oxidation of naphthalene and fluorene by toluene monooxygenases and engineered toluene 4-monooxygenases of Pseudomonas mendocina KR1. Biotechnol Bioeng. 2005 Apr 5;90(1):85-94.
PMID: 15723332
|
| naphthalene | 2-naphthol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Bentley WE, Wood TK. Regiospecific oxidation of naphthalene and fluorene by toluene monooxygenases and engineered toluene 4-monooxygenases of Pseudomonas mendocina KR1. Biotechnol Bioeng. 2005 Apr 5;90(1):85-94.
PMID: 15723332
|
| nitrobenzene | p-nitrophenol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| nitrobenzene | m-nitrophenol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| nitrobenzene | o-nitrophenol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| nitrobenzene | p-nitrophenol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| nitrobenzene | m-nitrophenol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| norcarane | 1-cyclohex-2-enylmethanol | Pseudomonas mendocina KR1 | + |
Moe LA, Hu Z, Deng D, Austin RN, Groves JT, Fox BG. Remarkable aliphatic hydroxylation by the diiron enzyme toluene 4-monooxygenase in reactions with radical or cation diagnostic probes norcarane, 1,1-dimethylcyclopropane, and 1,1-diethylcyclopropane. Biochemistry. 2004 Dec 21;43(50):15688-701. PubMed PMID:
PMID: 15595825
|
| o-cresol | methylhydroquinone | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| o-cresol | methylhydroquinone | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| o-cresol | 3-Methylbenzene-1,2-diol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| o-methoxy phenol | methoxyhydroquinone | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| o-methoxy phenol | 3-Methylbenzene-1,2-diol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Fishman A, Tao Y, Wood TK. Toluene 3-monooxygenase of Ralstonia pickettii PKO1 is a para-hydroxylating enzyme. J Bacteriol. 2004 May;186(10):3117-23. PubMed Central PMCID: PMC400597.
PMID: 15126473
|
| o-methoxy phenol | 4-methoxyresorcinol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| o-methoxy phenol | methoxyhydroquinone | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| o-methoxy phenol | 3-methoxycatechol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| o-methoxy phenol | 4-methoxyresorcinol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| o-xylene | 2-methyl benzyl alcohol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| o-xylene | 3,4-dimethylphenol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| p-cresol | 4-methylcatechol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone. J Bacteriol. 2004 Jul;186(14):4705-13. PubMed Central PMCID: PMC438599.
PMID: 15231803
|
| p-dichlorobenzene | | Pseudomonas mendocina KR1 | + |
Leahy JG, Tracy KD, Eley MH. Degradation of mixtures of aromatic and chloroaliphatic hydrocarbons by aromatic hydrocarbon-degrading bacteria. FEMS Microbiol Ecol. 2003 Mar 1;43(2):271-6. doi: 10.1111/j.1574-6941.2003.tb01067.x.
PMID: 19719688
|
| p-xylene | (4-methylphenyl)methanol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| p-xylene | 2,5-dimethylphenol | Pseudomonas mendocina KR1 | + |
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9.
PMID: 9280437
|
| phenetole | 2-ethoxyphenol | Pseudomonas mendocina KR1 | + |
Resnick, S. M., & Gibson, D. T. (1993). Biotransformation of anisole and phenetole by aerobic hydrocarbonoxidizing bacteria. Biodegradation, 4(3), 195–203.
doi: 10.1007/BF00695122 |
| phenetole | 3-ethoxyphenol | Pseudomonas mendocina KR1 | + |
Resnick, S. M., & Gibson, D. T. (1993). Biotransformation of anisole and phenetole by aerobic hydrocarbonoxidizing bacteria. Biodegradation, 4(3), 195–203.
doi: 10.1007/BF00695122 |
| phenetole | 4-ethoxyphenol | Pseudomonas mendocina KR1 | + |
Resnick, S. M., & Gibson, D. T. (1993). Biotransformation of anisole and phenetole by aerobic hydrocarbonoxidizing bacteria. Biodegradation, 4(3), 195–203.
doi: 10.1007/BF00695122 |
| phenol | catechol | Escherichia coli TG1 pBS(Kan)T4MO tmoABCDEF | + |
Tao Y, Fishman A, Bentley WE, Wood TK. Oxidation of benzene to phenol, catechol, and 1,2,3-trihydroxybenzene by toluene 4-monooxygenase of Pseudomonas mendocina KR1 and toluene 3-monooxygenase of Ralstonia pickettii PKO1. Appl Environ Microbiol. 2004 Jul;70(7):3814-20. PubMed Central
PMID: 15240250
|
| styrene | | Pseudomonas mendocina KR1 | + |
Leahy JG, Tracy KD, Eley MH. Degradation of mixtures of aromatic and chloroaliphatic hydrocarbons by aromatic hydrocarbon-degrading bacteria. FEMS Microbiol Ecol. 2003 Mar 1;43(2):271-6. doi: 10.1111/j.1574-6941.2003.tb01067.x.
PMID: 19719688
|
| tetrachloroethene | | Pseudomonas mendocina KR1 | + |
McClay K, Streger SH, Steffan RJ. Induction of toluene oxidation activity in Pseudomonas mendocina KR1 and Pseudomonas sp. strain ENVPC5 by chlorinated solvents and alkanes. Appl Environ Microbiol. 1995 Sep;61(9):3479-81. PubMed Central PMCID: PMC167628.
PMID: 7574658
|
| Toluene | p-cresol | Pseudomonas mendocina KR1 | + |
Whited GM, Gibson DT. Toluene-4-monooxygenase, a three-component enzyme system that catalyzes the oxidation of toluene to p-cresol in Pseudomonas mendocina KR1. J Bacteriol. 1991 May;173(9):3010-6. PubMed Central PMCID:
PMID: 2019563
|
| Toluene | p-cresol | Pseudomonas mendocina KR1 | + |
Whited GM, Gibson DT. Toluene-4-monooxygenase, a three-component enzyme system that catalyzes the oxidation of toluene to p-cresol in Pseudomonas mendocina KR1. J Bacteriol. 1991 May;173(9):3010-6. PubMed Central PMCID:
PMID: 2019563
|
| trans-dibromoethylene | | Pseudomonas mendocina KR1 | + |
McClay K, Fox BG, Steffan RJ. Chloroform mineralization by toluene-oxidizing bacteria. Appl Environ Microbiol. 1996 Aug;62(8):2716-22.
PMID: 8702263
|
| trichloroethene | | Pseudomonas mendocina KR1 | + |
McClay K, Streger SH, Steffan RJ. Induction of toluene oxidation activity in Pseudomonas mendocina KR1 and Pseudomonas sp. strain ENVPC5 by chlorinated solvents and alkanes. Appl Environ Microbiol. 1995 Sep;61(9):3479-81. PubMed Central PMCID: PMC167628.
PMID: 7574658
|
| xanthene | | Pseudomonas mendocina KR1 | + |
Oppenheim SF, Studts JM, Fox BG, Dordick JS. Aromatic hydroxylation catalyzed by toluene 4-monooxygenase in organic solvent/aqueous buffer mixtures. Appl Biochem Biotechnol. 2001 Mar;90(3):187-97.
PMID: 11318032
|
| xanthone | | Pseudomonas mendocina KR1 | + |
Oppenheim SF, Studts JM, Fox BG, Dordick JS. Aromatic hydroxylation catalyzed by toluene 4-monooxygenase in organic solvent/aqueous buffer mixtures. Appl Biochem Biotechnol. 2001 Mar;90(3):187-97.
PMID: 11318032
|
