11-Phenoxyundecanoic acid | 11-Hydroxy-11-phenoxyundecanoic acid | Escherichia coli pCYTEXp1 | + |
Wong TS, Wu N, Roccatano D, Zacharias M, Schwaneberg U. Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. J Biomol Screen. 2005 Apr;10(3):246-52. PMID: 15809320
|
12-methyltetradecanoic acid | 11-Hydroxy-12-methyltetradecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
12-methyltetradecanoic acid | 12-Hydroxy-12-methyltetradecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
12-methyltetradecanoic acid | 13-Hydroxy-12-methyltetradecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
13-methyltetradecanoic acid | 11-Hydroxy-13-methyltetradecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
13-methyltetradecanoic acid | 12-Hydroxy-13-methyltetradecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
13-methyltetradecanoic acid | 13-Hydroxy-13-methyltetradecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
14-Methylhexadecanoic acid | 13-Hydroxy-14-methylhexadecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
14-Methylhexadecanoic acid | 14-Hydroxy-14-methylhexadecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
14-Methylhexadecanoic acid | 15-Hydroxy-14-methylhexadecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
15-Methylhexadecanoic acid | 13-Hydroxy-15-methylhexadecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
15-Methylhexadecanoic acid | 14-Hydroxy-15-methylhexadecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
15-Methylhexadecanoic acid | 15-Hydroxy-15-methylhexadecanoic acid | Bacillus megaterium 14581 | + |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chem Commun (Camb). 2006 Jun 14;(22):2353-5. PMID: 16733577
|
2-Methylbenzofuran | | Escherichia coli pCYTEXp1 | + |
Wong TS, Wu N, Roccatano D, Zacharias M, Schwaneberg U. Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. J Biomol Screen. 2005 Apr;10(3):246-52. PMID: 15809320
|
2-Phenoxytoluene | | Escherichia coli pCYTEXp1 | + |
Wong TS, Wu N, Roccatano D, Zacharias M, Schwaneberg U. Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. J Biomol Screen. 2005 Apr;10(3):246-52. PMID: 15809320
|
3-Phenoxytoluene | | Escherichia coli pCYTEXp1 | + |
Wong TS, Wu N, Roccatano D, Zacharias M, Schwaneberg U. Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. J Biomol Screen. 2005 Apr;10(3):246-52. PMID: 15809320
|
4-Chromanone | | Escherichia coli pCYTEXp1 | + |
Wong TS, Wu N, Roccatano D, Zacharias M, Schwaneberg U. Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. J Biomol Screen. 2005 Apr;10(3):246-52. PMID: 15809320
|
Arachidonic acid | 18-hydroxyarachidonic acid | Bacillus megaterium 14581 | + |
Celik A, Sperandio D, Speight RE, Turner NJ. Enantioselective epoxidation of linolenic acid catalysed by cytochrome P450(BM3) from Bacillus megaterium. Org Biomol Chem. 2005 Aug 7;3(15):2688-90. PMID: 16032346
|
benzofuran | | Escherichia coli pCYTEXp1 | + |
Wong TS, Wu N, Roccatano D, Zacharias M, Schwaneberg U. Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. J Biomol Screen. 2005 Apr;10(3):246-52. PMID: 15809320
|
bromide | | Bacillus megaterium 14581 | + |
Oliver CF, Modi S, Primrose WU, Lian LY, Roberts GC. Engineering the substrate specificity of Bacillus megaterium cytochrome P-450 BM3: hydroxylation of alkyl trimethylammonium compounds. Biochem J. 1997 Oct 15;327 ( Pt 2):537-44. PubMed Central PMCID: PMC1218827. PMID: 9359427
|
bromide | | Bacillus megaterium 14581 | + |
Ost TW, Miles CS, Murdoch J, Cheung Y, Reid GA, Chapman SK, Munro AW. Rational re-design of the substrate binding site of flavocytochrome P450 BM3. FEBS Lett. 2000 Dec 8;486(2):173-7. PMID: 11113461
|
cis-12-octadecenoate | 15-hydroxy-cis-12-octadecenoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-12-octadecenoate | 16-hydroxy-cis-12-octadecenoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-12-octadecenoate | 17-hydroxy-cis-12-octadecenoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-5-tetradecanoate | 11-Hydroxytetradecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-5-tetradecanoate | 12-Hydroxytetradecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-5-tetradecanoate | 13-Hydroxytetradecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-5-tetradecanoate | 11-Hydroxytetradecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-5-tetradecanoate | 12-Hydroxytetradecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-5-tetradecanoate | 13-Hydroxytetradecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-5-tetradecanoate | | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-hexadecanoate | 13-Hydroxyhexadecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-hexadecanoate | 14-Hydroxyhexadecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-hexadecanoate | 15-Hydroxyhexadecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-hexadecanoate | 13-Hydroxyhexadecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-hexadecanoate | 14-Hydroxyhexadecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-hexadecanoate | 15-Hydroxyhexadecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-hexadecanoate | 12-hydroxy-cis-9-hexadecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-hexadecanoate | 13-hydroxy-cis-9-hexadecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-hexadecanoate | 14-hydroxy-cis-9-hexadecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-hexadecanoate | 15-hydroxy-cis-9-hexadecanoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-octadecanoate | 15-hydroxy-cis-9-octadecenoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-octadecanoate | 16-hydroxy-cis-9-octadecenoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
cis-9-octadecanoate | 17-hydroxy-cis-9-octadecenoate | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
decanoic acid | | Bacillus megaterium 14581 | + |
Farinas, E. T., Schwaneberg, U., Glieder, A., & Arnold, F. H. (2001). Directed Evolution of a Cytochrome P450 Monooxygenase for Alkane Oxidation. Advanced Synthesis & Catalysis, 343(6-7), 601–606.
doi: 10.1002/1615-4169(200108)343:6/7<601::AID-ADSC601>3.0.CO;2-9 |
decanoic acid | | Bacillus megaterium 14581 | + |
Ost TW, Miles CS, Murdoch J, Cheung Y, Reid GA, Chapman SK, Munro AW. Rational re-design of the substrate binding site of flavocytochrome P450 BM3. FEBS Lett. 2000 Dec 8;486(2):173-7. PMID: 11113461
|
Diphenylether | | Escherichia coli pCYTEXp1 | + |
Wong TS, Wu N, Roccatano D, Zacharias M, Schwaneberg U. Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. J Biomol Screen. 2005 Apr;10(3):246-52. PMID: 15809320
|
dodecanoic acid | 9-hydroxydodecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
dodecanoic acid | 10-hydroxydodecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
dodecanoic acid | 11-hydroxydodecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
dodecanoic acid | | Bacillus megaterium 14581 | + |
Appel D, Lutz-Wahl S, Fischer P, Schwaneberg U, Schmid RD. A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes. J Biotechnol. 2001 Jun 15;88(2):167-71. PMID: 11403851
|
dodecanoic acid | | Bacillus megaterium 14581 | + |
Appel D, Lutz-Wahl S, Fischer P, Schwaneberg U, Schmid RD. A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes. J Biotechnol. 2001 Jun 15;88(2):167-71. PMID: 11403851
|
dodecanoic acid | | Bacillus megaterium 14581 | + |
Appel D, Lutz-Wahl S, Fischer P, Schwaneberg U, Schmid RD. A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes. J Biotechnol. 2001 Jun 15;88(2):167-71. PMID: 11403851
|
dodecanol | 1,9-dodecanediol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
dodecanol | 1,10-dodecanediol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
dodecanol | 1,11-dodecanediol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
dodecylamide | 9-hydroxydodecylamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
dodecylamide | 10-hydroxydodecylamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
dodecylamide | 11-hydroxydodecylamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
eicosatrienoic acid | 17-hydroxyeicosatetraenoic acid | Bacillus megaterium 14581 | + |
Capdevila JH, Wei S, Helvig C, Falck JR, Belosludtsev Y, Truan G, Graham-Lorence SE, Peterson JA. The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3. J Biol Chem. 1996 Sep 13;271(37):22663-71. PMID: 8798438
|
eicosatrienoic acid | 18-hydroxyeicosatetraenoic acid | Bacillus megaterium 14581 | + |
Capdevila JH, Wei S, Helvig C, Falck JR, Belosludtsev Y, Truan G, Graham-Lorence SE, Peterson JA. The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3. J Biol Chem. 1996 Sep 13;271(37):22663-71. PMID: 8798438
|
eicosatrienoic acid | 19-hydroxyeicosatetraenoic acid | Bacillus megaterium 14581 | + |
Capdevila JH, Wei S, Helvig C, Falck JR, Belosludtsev Y, Truan G, Graham-Lorence SE, Peterson JA. The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3. J Biol Chem. 1996 Sep 13;271(37):22663-71. PMID: 8798438
|
ethane | | Bacillus megaterium 14581 | + |
Meinhold P, Peters MW, Chen MM, Takahashi K, Arnold FH. Direct conversion of ethane to ethanol by engineered cytochrome P450 BM3. Chembiochem. 2005 Oct;6(10):1765-8. PMID: 16080215
|
heptadecanoic acid | 14-hydroxyheptadecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
heptadecanoic acid | 15-hydroxyheptadecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
heptadecanoic acid | 16-hydroxyheptadecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
hexadecanol | 1,13-hexadecanediol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
hexadecanol | 1,14-hexadecanediol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
hexadecanol | 1,15-hexadecanediol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
hexadecyl-trimethyl-ammonium bromide | | Bacillus megaterium 14581 | + |
Ost TW, Miles CS, Murdoch J, Cheung Y, Reid GA, Chapman SK, Munro AW. Rational re-design of the substrate binding site of flavocytochrome P450 BM3. FEBS Lett. 2000 Dec 8;486(2):173-7. PMID: 11113461
|
hexanoic acid | | Bacillus megaterium 14581 | + |
Ost TW, Miles CS, Murdoch J, Cheung Y, Reid GA, Chapman SK, Munro AW. Rational re-design of the substrate binding site of flavocytochrome P450 BM3. FEBS Lett. 2000 Dec 8;486(2):173-7. PMID: 11113461
|
naphthalene | | Escherichia coli pCYTEXp1 | + |
Appel D, Lutz-Wahl S, Fischer P, Schwaneberg U, Schmid RD. A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes. J Biotechnol. 2001 Jun 15;88(2):167-71. PMID: 11403851
|
octadecanoic acid | 15-hydroxyoctadecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
octadecanoic acid | 16-hydroxyoctadecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
octadecanoic acid | 17-hydroxyoctadecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
octanoic acid | | Bacillus megaterium 14581 | + |
Farinas, E. T., Schwaneberg, U., Glieder, A., & Arnold, F. H. (2001). Directed Evolution of a Cytochrome P450 Monooxygenase for Alkane Oxidation. Advanced Synthesis & Catalysis, 343(6-7), 601–606.
doi: 10.1002/1615-4169(200108)343:6/7<601::AID-ADSC601>3.0.CO;2-9 |
octanoic acid | | Bacillus megaterium 14581 | + |
Farinas, E. T., Schwaneberg, U., Glieder, A., & Arnold, F. H. (2001). Directed Evolution of a Cytochrome P450 Monooxygenase for Alkane Oxidation. Advanced Synthesis & Catalysis, 343(6-7), 601–606.
doi: 10.1002/1615-4169(200108)343:6/7<601::AID-ADSC601>3.0.CO;2-9 |
octanoic acid | | Bacillus megaterium 14581 | + |
Farinas, E. T., Schwaneberg, U., Glieder, A., & Arnold, F. H. (2001). Directed Evolution of a Cytochrome P450 Monooxygenase for Alkane Oxidation. Advanced Synthesis & Catalysis, 343(6-7), 601–606.
doi: 10.1002/1615-4169(200108)343:6/7<601::AID-ADSC601>3.0.CO;2-9 |
octanoic acid | 3-octanol | Bacillus megaterium 14581 | + |
Farinas, E. T., Schwaneberg, U., Glieder, A., & Arnold, F. H. (2001). Directed Evolution of a Cytochrome P450 Monooxygenase for Alkane Oxidation. Advanced Synthesis & Catalysis, 343(6-7), 601–606.
doi: 10.1002/1615-4169(200108)343:6/7<601::AID-ADSC601>3.0.CO;2-9 |
p-nitrophenoxydecanoic acid | | Bacillus megaterium 14581 | + |
Schwaneberg U, Schmidt-Dannert C, Schmitt J, Schmid RD. A continuous spectrophotometric assay for P450 BM-3, a fatty acid hydroxylating enzyme, and its mutant F87A. Anal Biochem. 1999 May 1;269(2):359-66. PMID: 10222011
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p-nitrophenoxydecanoic acid | | Bacillus megaterium 14581 | + |
Schwaneberg U, Schmidt-Dannert C, Schmitt J, Schmid RD. A continuous spectrophotometric assay for P450 BM-3, a fatty acid hydroxylating enzyme, and its mutant F87A. Anal Biochem. 1999 May 1;269(2):359-66. PMID: 10222011
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p-nitrophenoxyhexanoic acid | | Bacillus megaterium 14581 | + |
Schwaneberg U, Schmidt-Dannert C, Schmitt J, Schmid RD. A continuous spectrophotometric assay for P450 BM-3, a fatty acid hydroxylating enzyme, and its mutant F87A. Anal Biochem. 1999 May 1;269(2):359-66. PMID: 10222011
|
p-nitrophenoxyhexanoic acid | | Bacillus megaterium 14581 | + |
Schwaneberg U, Schmidt-Dannert C, Schmitt J, Schmid RD. A continuous spectrophotometric assay for P450 BM-3, a fatty acid hydroxylating enzyme, and its mutant F87A. Anal Biochem. 1999 May 1;269(2):359-66. PMID: 10222011
|
p-nitrophenoxyoctanoic acid | | Bacillus megaterium 14581 | + |
Schwaneberg U, Schmidt-Dannert C, Schmitt J, Schmid RD. A continuous spectrophotometric assay for P450 BM-3, a fatty acid hydroxylating enzyme, and its mutant F87A. Anal Biochem. 1999 May 1;269(2):359-66. PMID: 10222011
|
p-nitrophenoxyoctanoic acid | | Bacillus megaterium 14581 | + |
Schwaneberg U, Schmidt-Dannert C, Schmitt J, Schmid RD. A continuous spectrophotometric assay for P450 BM-3, a fatty acid hydroxylating enzyme, and its mutant F87A. Anal Biochem. 1999 May 1;269(2):359-66. PMID: 10222011
|
p-nitrophenoxyundecanoic acid | | Bacillus megaterium 14581 | + |
Schwaneberg U, Schmidt-Dannert C, Schmitt J, Schmid RD. A continuous spectrophotometric assay for P450 BM-3, a fatty acid hydroxylating enzyme, and its mutant F87A. Anal Biochem. 1999 May 1;269(2):359-66. PMID: 10222011
|
p-nitrophenoxyundecanoic acid | | Bacillus megaterium 14581 | + |
Schwaneberg U, Schmidt-Dannert C, Schmitt J, Schmid RD. A continuous spectrophotometric assay for P450 BM-3, a fatty acid hydroxylating enzyme, and its mutant F87A. Anal Biochem. 1999 May 1;269(2):359-66. PMID: 10222011
|
palmitamide | 13-hydroxypalmitamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
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palmitamide | 14-hydroxypalmitamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
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palmitamide | 15-hydroxypalmitamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
pentadecanoic acid | 12-hydroxypentadecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
pentadecanoic acid | 13-hydroxypentadecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
pentadecanoic acid | 14-hydroxypentadecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
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pentadecanol | 1,12-pentadecanediol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
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pentadecanol | 1,13-pentadecanediol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
pentadecanol | 1,14-pentadecanediol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
pentadecylamide | 12-hydroxypentadecylamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
pentadecylamide | 13-hydroxypentadecylamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
pentadecylamide | 14-hydroxypentadecylamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
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phenetole | | Escherichia coli pCYTEXp1 | + |
Wong TS, Wu N, Roccatano D, Zacharias M, Schwaneberg U. Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. J Biomol Screen. 2005 Apr;10(3):246-52. PMID: 15809320
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Phenoxyoctanol | | Escherichia coli pCYTEXp1 | + |
Wong TS, Wu N, Roccatano D, Zacharias M, Schwaneberg U. Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. J Biomol Screen. 2005 Apr;10(3):246-52. PMID: 15809320
|
Phenylallylether | | Escherichia coli pCYTEXp1 | + |
Wong TS, Wu N, Roccatano D, Zacharias M, Schwaneberg U. Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. J Biomol Screen. 2005 Apr;10(3):246-52. PMID: 15809320
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propane | | Bacillus megaterium 14581 | + |
Meinhold P, Peters MW, Chen MM, Takahashi K, Arnold FH. Direct conversion of ethane to ethanol by engineered cytochrome P450 BM3. Chembiochem. 2005 Oct;6(10):1765-8. PMID: 16080215
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styrene | (S)-styrene oxide | Bacillus megaterium 14581 | + |
Eiben S, Kaysser L, Maurer S, Kühnel K, Urlacher VB, Schmid RD. Preparative use of isolated CYP102 monooxygenases -- a critical appraisal. J Biotechnol. 2006 Aug 5;124(4):662-9. Review. PMID: 16716428
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tetradecanol | 1,11-tetradecandiol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tetradecanol | 1,12-tetradecandiol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tetradecanol | 1,13-tetradecandiol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tetradecylamide | 11-hydroxytetradecylamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tetradecylamide | 12-hydroxytetradecylamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tetradecylamide | 13-hydroxytetradecylamide | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tridecanoic acid | 10-hydroxytridecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tridecanoic acid | 11-hydroxytridecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tridecanoic acid | 12-hydroxytridecanoic acid | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tridecanol | 1,10-tridecandiol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tridecanol | 1,11-tridecandiol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|
tridecanol | 1,12-tridecandiol | Bacillus megaterium 14581 | + |
Miura Y, Fulco AJ. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta. 1975 Jun 23;388(3):305-17. PMID: 805599
|