RAPID | for identifying and exploiting enzyme catalysis.

Product	Enzyme	Expression System	Reference
(4R)-chroman-4-ol	Toluene 2,3-dioxygenase	Pseudomonas putida UV4	+
Boyd, D. R., Sharma, N. D., Bowers, N. I., Boyle, R., Harrison, J. S., Lee, K., … Gibson, D. T. (2003). Stereochemical and mechanistic aspects of dioxygenase-catalysed benzylic hydroxylation of indene and chromane substrates. Organic & Biomolecular Chemistry, 1(8), 1298–1307. doi: 10.1039/b300898c
4-Chromanone	Toluene 2,3-dioxygenase	Pseudomonas putida UV4	+
Boyd, D. R., Sharma, N. D., Bowers, N. I., Boyle, R., Harrison, J. S., Lee, K., … Gibson, D. T. (2003). Stereochemical and mechanistic aspects of dioxygenase-catalysed benzylic hydroxylation of indene and chromane substrates. Organic & Biomolecular Chemistry, 1(8), 1298–1307. doi: 10.1039/b300898c