RAPID | for identifying and exploiting enzyme catalysis.

Substrate	Enzyme	Expression System	Reference
m-xylene	Toluene 4-monooxygenase	Pseudomonas mendocina KR1	+
Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG. Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 1997 Aug 5;36(31):9283-9. PMID: 9280437
m-xylene	Toluene 2,3-dioxygenase	Pseudomonas putida F39/D	+
Gibson DT, Mahadevan V, Davey JF. Bacterial metabolism of para- and meta-xylene: oxidation of the aromatic ring. J Bacteriol. 1974 Sep;119(3):930-6. PubMed Central PMCID: PMC245701. PMID: 4850728