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Substrate	Enzyme	Expression System	Reference
1-methylpyridin-2-one	Toluene 2,3-dioxygenase	Pseudomonas putida UV4	+
Boyd, D. R., Sharma, N. D., Modyanova, L. V., Carroll, J. G., Malone, J. F., Allen, C. C., … Dalton, H. (2002). Dioxygenase-catalyzed cis -dihydroxylation of pyridine-ring systems . Canadian Journal of Chemistry, 80(6), 589–600. doi: 10.1139/v02-062
1-methylpyridin-2-one	Naphthalene 1,2-dioxygenase	Escherichia coli JM109 pDTG141	+
Modyanova, L., & Azerad, R. (2000). Dioxygenase-catalysed formation of dihydrodiol metabolites of N-methyl-2-pyridone. Tetrahedron Letters, 41(20), 3865–3869. doi: 10.1016/S0040-4039(00)00541-4